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Catalog Number | orb1710655 |
---|---|
Category | Small Molecules |
Description | (1α,1'S,4β)-Lanabecestat |
CAS Number | 1384082-96-5 |
Purity | 98.00% |
MW | 412.53 |
SMILES | CC1=N[C@@]2([C@]3(CC=4C2=CC(=CC4)C=5C=C(C#CC)C=NC5)CC[C@@H](OC)CC3)N=C1N |
Formula | C26H28N4O |
Biological Activity | (1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay), respectively. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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