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11β-Prostaglandin E2

SKU: orb1693997

Description

11β-PGE2, the C-11 epimer of PGE2, acts as a moderate inhibitor of PGE2 binding to its receptor (Ki ~53 nM) and transporter (Ki ~56 nM). It also stimulates bone resorption in rat models at concentrations from 10⁻⁸ to 10⁻⁶ M, making it a useful tool for studying prostaglandin signaling in bone metabolism and neuroendocrine research.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number38310-90-6
MW352.47
FormulaC20H32O5
SMILESC(/C=C\CCCC(O)=O)[C@@H]1[C@@H](/C=C/[C@H](CCCCC)O)[C@@H](O)CC1=O
TargetProstaglandin Receptor,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information