11α-O-Benzoyl-12β-O-acetyltenacigenin B

SKU: orb2663461

Description

11α-O-Benzoyl-12β-O-acetyltenacigenin B is a P-glycoprotein (Pgp) inhibitor derived from Marsdenia tenacissima. It reverses multidrug resistance in vitro, as shown in Pgp-overexpressing HepG2/Dox cells, supporting its application in cancer research, particularly in overcoming chemoresistance.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 154022-52-3
• MW: 510.62
• Formula: C₃₀H₃₈O₇
• SMILES: C[C@@]12[C@@]3([C@@]4(O3)[C@]([C@H](OC(=O)C5=CC=CC=C5)[C@H]1OC(C)=O)([C@]6(C)[C@@](CC4)(C[C@@H](O)CC6)[H])[H])CC[C@H]2C(C)=O
• Target: P-gp

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44561449