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10-Nitrocamptothecin

SKU: orb3211195

Description

10-Nitrocamptothecin is a topoisomerase I (Topoisomerase I) inhibitor with an IC50 of 0.64 μM. It interferes with the formation of the cleavable complex, thereby inhibiting the activity of topoisomerase I. 10-Nitrocamptothecin is applicable in cancer research.

Images & Validation

Key Properties

CAS Number86639-62-5
MW393.35
FormulaC20H15N3O6
SMILESO=C1N2C(C=3C(C2)=CC=4C(N3)=CC=C(N(=O)=O)C4)=CC5=C1COC(=O)[C@@]5(CC)O
TargetTopoisomerase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information