10-Methyl-10-deazaaminopterin

SKU: orb1702658

Description

10-Methyl-10-deazaaminopterin is a synthetic folate analog with demonstrated antitumor properties. It functions as a potent inhibitor of dihydrofolate reductase (DHFR), disrupting nucleotide synthesis. This mechanism supports its investigation in cancer research, including studies on tumor cell proliferation in both in vitro and in vivo experimental models.

Research Area

Cell Biology

Key Properties

• CAS Number: 80576-77-8
• MW: 453.45
• Formula: C₂₁H₂₃N₇O₅
• SMILES: NC=1C2=C(N=CC(CC(C)C3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)N=C(N)N1
• Target: Antifolate,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

133507