10-Methoxy-canthin-6-one

SKU: orb2665032

Description

10-Methoxy-canthin-6-one is a DNA-intercalating agent that induces DNA damage, leading to G2/M cell cycle arrest and subsequent differentiation in acute myeloid leukemia (AML) and leukemia stem cells (LSCs). This small molecule is a valuable research tool for studying myeloid differentiation and p38 MAPK signaling in both in vitro and in vivo leukemia models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 86293-40-5
• MW: 250.25
• Formula: C₁₅H₁₀N₂O₂
• SMILES: O=C1C=CC2=NC=CC=3C4=CC(OC)=CC=C4N1C23
• Target: p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

158928