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1-Deoxynojirimycin

SKU: orb1223212

Description

1-Deoxynojirimycin is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.

Images & Validation

Key Properties

CAS Number19130-96-2
MW163.17
Purity>98% (HPLC)
FormulaC6H13NO4
SMILESC1[C@@H]([C@H]([C@@H]([C@H](N1)CO)O)O)O
TargetPPAR
SolubilityH2O : ≥ 34 mg/mL; 208.37 mM

Bioactivity

In Vivo
Animal model: db/db mice. Dosage: 20, 40, 80 mg/kg. Administration: Intravenously; daily for four weeks. Result: Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Duvoglustat

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Protocol Information

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