1-Caffeoylquinic acid

SKU: orb1297584

Description

1-Caffeoylquinic acid, a key biosynthetic intermediate in lignin formation, exhibits antioxidant and anti-influenza virus properties. Research indicates it modulates postprandial glucose absorption, making it relevant for metabolic and pharmacological studies in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 1241-87-8
• MW: 354.31
• Purity: 98.77% (May vary between batches)
• Formula: C₁₆H₁₈O₉
• SMILES: O[C@@H]1C[C@](C[C@@H](O)[C@H]1O)(OC(=O)\C=C\c1ccc(O)c(O)c1)C(O)=O
• Target: PD-1/PD-L1,NF-κB
• Solubility: DMSO:9 mg/mL (25.4 mM)

Bioactivity

• Target IC50:
  1-Caffeoylquinic acid:Ki: 0.002 μM
• In Vitro:
  Thirteen phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, 1-Caffeoylquinic acid, 5-p-coumaroylquinic acid, isoorientin-2'-O-rhamnoside, isoorientin, orientin-2'-O-rhamnoside, orientin, 1-p-coumaroylquinic acid, vitexin-2'-O-rhamnoside, isovitexin-2'-O-rhamnoside, vitexin and isovitexin) were identified in T. hemsleyanum leaves for the first time, and six of them were quantified using a combination of LC-QTOF-MS and LC-QqQ-MS techniques. It was found that 80% methanol extract exhibited the highest antioxidant activities.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

1 Caffeoylquinic acid, 1Caffeoylquinic acid, 1-Caffeoylquinic acid, Inhibitor, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, NFκB, NF-kB, NFkB, inhibit

Compound Identifiers

PubChem CID

10155076