WIZ degrader 3

SKU: orb2663933

Description

WIZ degrader 3 (Compound 29) is a potent small molecule that degrades the WIZ protein (AC50 = 6.4 nM) and induces fetal hemoglobin (HbF) expression (EC50 = 45 nM). It serves as a valuable research tool for investigating potential therapeutic strategies for β-hemoglobinopathies like sickle cell disease and β-thalassemia in both cellular and animal models.

Key Properties

• CAS Number: 2839637-72-6
• MW: 357.41
• Formula: C₁₈H₂₃N₅O₃
• SMILES: C(C=1C=C2C(=NOC2=CC1)N3C(=O)NC(=O)CC3)N4C[C@H](C)N(C)CC4

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172419471