HbF inducer 2

SKU: orb2646072

Description

Compound dWIZ-2 is an orally active PROTAC molecular glue degrader of the WIZ transcription factor (DC50 = 13 nM). It potently induces fetal hemoglobin (HbF) expression (EC50 = 100 nM) and serves as a valuable research tool for studying hemoglobinopathies like sickle cell disease in both cellular and animal models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2654011-51-3
• MW: 385.46
• Purity: 99.90% (May vary between batches)
• Formula: C₂₁H₂₇N₃O₄
• SMILES: O=C1N(CC=2C1=CC=C(OC[C@@H]3N(CC)CCCC3)C2)C4C(=O)NC(=O)CC4
• Target: Molecular Glues

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156500472