WHSC1 isoform3 (N) Antibody, Rabbit Polyclonal

SKU: orb67152

Description

Rabbit polyclonal to WHSC1 isoform 3.Wolf-Hirschhorn syndrome candidate 1 protein (WHSC1) is a probable histone methyltransferasewhich may act as a transcription regulator that binds DNA and suppresses IL5 transcription. WHSC1contains four domains present in other developmental proteins: a PWWP domain, an HMG box, aSET domain and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion ofthe distal short arm of chromosome 4. The WHSC1 gene maps to the 165 kb WHS critical region andhas also been implicated in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas.Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Research Area

Cancer, Epigenetics

Images & Validation

• Tested Applications: WB
• Dilution Range: WB:1:500-1:1000
• Reactivity: Human

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: N-terminal region of human WHSC1
• Molecular Weight: 152
• Purity: Affinity purification
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.01% NaN3
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

anti-WHSC1 isoform 3 antibody,anti-Probable histonelysine Nmethyltransferase NSD2 antibody,anti-Multiple myeloma SET domaincontaining protein antibody,anti- Nuclear SET domaincontaining protein 2 antibody,anti-Protein trithorax5 antibody,anti-WolfHirschhorn syndrome candidate 1 protein antibody,anti-KIAA1090 antibody,anti-MMSET antibody,anti-NSD2 antibody,anti-TRX5 antibody

Western blot analysis of total cell extracts from human Hela using WHSC1 isoform 3 antibody

Quick Database Links

UniProt

O96028