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VSA 1

SKU: orb3145002

Description

VSA 1 is a semisynthetic analog of QS-21, serving as a saponin adjuvant. It enhances antigen-specific IgG1 and IgG2a immune responses in BALB/c mice, indicating a mixed Th1/Th2 immune response. VSA 1 significantly increases vaccine efficacy following initial immunization and boosts homologous protection.

Images & Validation

Key Properties

CAS Number2489675-55-8
MW1841.08
FormulaC88H145NO39
SMILESC(O[C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3[C@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)CO4)[C@H](O)[C@@H](CO)O3)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)CO5)[C@H](C)O2)[C@@H](O)[C@@H](O)[C@@H](C)O1)(=O)[C@]67[C@](C=8[C@@](C)(CC6)[C@@]9(C)[C@](CC8)([C@]%10(C)[C@@](CC9)([C@@](C=O)(C)[C@@H](O[C@H]%11[C@H](O[C@@H]%12O[C@H](CO)[C@H](O)[C@H](O)[C@H]%12O)[C@@H](O[C@H]%13[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O%13)[C@H](O)[C@@H](C(NCCCCCCCCCCCC)=O)O%11)CC%10)[H])[H])(CC(C)(C)CC7)[H]
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

VSA 1 (orb3145002)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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