Unifiram

SKU: orb1940299

Description

Unifiram is a cognition-enhancer. Unifiram induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the rat hippocampal CA1 region (EC50= 27 nM) and increases acetylcholine (ACh) release in the rat cerebral cortex.(In Vivo):Unifiram (0.1 mg kg 1 i.p.) was able to prevent amnesia induced by scopolamine (0.8 mg kg 1 i.p.) in the rat Morris watermaze test. In the rat social learning test, Unifiram (0.1 mg kg 1 i.p.) injected in adults rats reduced the duration of active exploration of the familiar partner in the second session of the test. Unifiram, similarly to piracetam, reduced the duration of hypnosis induced by pentobarbital. At the highest effective doses, the investigated compound did not impair motor coordination (rota rod test), nor modified spontaneous (Animex).

Key Properties

• CAS Number: 272786-64-8
• MW: 298.33
• Purity: >98% (HPLC)
• Formula: C₁₃H₁₅FN₂O₃S
• SMILES: Fc1ccc(cc1)S(=O)(=O)N1CCN2C(CCC2=O)C1
• Target: 15-PGDH

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

15-PGDH