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Catalog Number | orb532327 |
---|---|
Category | Tools |
Description | UDP-GalNAz |
Form/Appearance | solid; Color: colorless to white |
Purity | ≥ 95% (HPLC) |
MW | Theoretical MW: 648.37 g/mol (free acid); Detected MW: 648.08 g/mol (free acid) |
SMILES | [C@H]1([C@H](C(O[C@@H]([C@@H]1O)CO)OP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1c(=O)[nH]c(=O)cc1)O)O)NC(=O)CN=[N+]=[N-])O |
Formula | C17H26N6O17P2 |
Hazard Information | Non-Toxic |
Solubility (25°C) | water, aqueous buffer pH 7-7.5 |
Storage | store at -20 °C |
Note | For research use only |
Application notes | Transfer of GalNAz moiety to GalNAc residues of proteins and mono-clonal antibodies with ß1, 4-galactosyltranferase mutant Y289L-Gal-T1. The azide-functionalized target can subsequently be detected via Cu(I)-catalyzed or Cu(I)-free Click Chemistry that offers the choice to introduce a Biotin group (via Azides of Biotin or DBCO-containing Biotin, respectively) for subsequent purification tasks or a fluorophore (via Azides of fluorescent dyes or DBCO-containing fluorescent dyes, respectively) for subsequent mi-croscopic imaging. < br>< b>Spectroscopic Propertie: λmax 262 nm, ε 10.0 L mmol-1cm-1 (Tris-HCl, pH 7.5). |
Expiration Date | 12 months from date of receipt. |