TRH Receptor Antibody

SKU: orb248119

Description

Thyrotropin-releasing hormone (TRH) is produced by tissues of the nervous system and to a lesser degree, pancreas, testis, adrenal gland and lymphoid organs. There are two types of TRH in rodents, TRH1 and 2, but only TRH1 in humans. In cells of the nervous system, it is a neurotransmitter, acting via its receptor, TRH receptor, to stimulate phosphoinositide-specific phospholipase C, which stimulates phosphatidylinositol hydrolysis to form inositol triphosphate.

Images & Validation

• Tested Applications: WB
• Dilution Range: Western blot: 1-3ug/ml
• Reactivity: Human
• Application Notes:
  Provided assay concentrations are suggestions only, TRH receptor antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment from the C-terminal region of TRH receptor was used as the immunogen for this antibody.
• Purification: Protein A purified antibody
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Western blot testing of human samples with TRH receptor antibody at 1 ug/ml.