Tetrabenazine

SKU: orb1310352

Description

Tetrabenazine (Ro 1-9569) is a vesicular monoamine transporter 2 (VMAT2) inhibitor historically used as an antipsychotic and for movement disorders. It serves as a high-affinity research tool for studying vesicular neurotransmitter transport in both in vitro binding assays and in vivo models of hyperkinetic conditions.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 58-46-8
• MW: 317.42
• Purity: 99.88%
• Formula: C₁₉H₂₇NO₃
• SMILES: O(C)C=1C=C2[C@]3(N(C[C@H](CC(C)C)C(=O)C3)CCC2=CC1OC)[H]
• Target: Monoamine Transporter,Dopamine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.3 mM);DMSO:18.33 mg/mL (57.75 mM);Ethanol:32 mg/mL (100.81 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

D2, Dopamine Receptor, DopamineReceptor, Aggression, inhibit, MonoamineTransporter, Monoamine Transporter, Inhibitor, Huntington's disease, Synaptic vesicular amine transporter, Tetrabenazine, Ro 1-9569, Xenazine, VMAT2 inhibitor, Tremor

Compound Identifiers

PubChem CID

11634155