Tetrabenazine Racemate

SKU: orb1304107

Description

Tetrabenazine Racemate (Rubigen) is a reversible, high-affinity VMAT-2 inhibitor that blocks monoamine uptake into synaptic vesicles. It is widely used in neuroscience research to study vesicular neurotransmission in models of Huntington's disease and related hyperkinetic movement disorders, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 718635-93-9
• MW: 317.42
• Purity: 98.86% (May vary between batches)
• Formula: C₁₉H₂₇NO₃
• SMILES: COc1cc2CCN3CC(CC(C)C)C(=O)CC3c2cc1OC
• Target: Monoamine Transporter
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.3 mM);DMSO:55 mg/mL (173.27 mM)

Bioactivity

• In Vivo:
  BMS-663068 has good antiviral activity in subjects infected with virus shown to be susceptible (IC50, <100 nM) to the agent.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ro 1-9569 Racemate, Ro 1-9569, Rubigen, TETRABENAZINE, Tetrabenazine Racemate, VMAT-2, Nitoman, Monoamine Transporter, MonoamineTransporter, inhibit, Inhibitor

Compound Identifiers

PubChem CID

6018