Tanezumab Antibody

SKU: orb2278745

Description

Tanezumab is a humanized monoclonal antibody that alleviates pain by selectively targeting nerve growth factor (NGF). It blocks NGF's interaction with its TrkA and p75 receptors, inhibiting pain signal transduction. This mechanism has been investigated in preclinical models and clinical trials for conditions like osteoarthritis and chronic neuropathic pain.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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Target	Trk receptor
Molecular Weight	145.43 kDa
Purity	95.90% (May vary between batches)
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Concentration	5.51 mg/mL
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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PF-4383119, RN 624, Tanezumab

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Quick Database Links

Gene Symbol

Trk receptor

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