T863

• Catalog Number: orb1302657
• Category: Small Molecules
• Description: T863
• CAS Number: 701232-20-4
• Purity: 99.88%
• MW: 394.47
• SMILES: CC1(C)C(=NC=2C(O1)=NC=NC2N)C3=CC=C(C=C3)[C@@H]4CC[C@@H](CC(O)=O)CC4
• Formula: C₂₂H₂₆N₄O₃
• Biological Activity: T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that interacts with the acyl-CoA binding site of DGAT1, and inhibits triacylglycerol synthesis in cells. IC50 value: Target: DGAT1 T863 (DGAT-3) causes weight loss, reduction in serum and liver triglycerides, and improved insulin sensitivity in obese mice.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.