Sodium gualenate

SKU: orb1220572

Description

Sodium gualenate (Guaiazulenesulfonate sodium) a hydrophilic derivative of guaiazulene (GA) is an unstable compound. It has anti-inflammatory and wound-healing effects. (In Vitro):Sodium gualenate is an unstable compound, which is gradually decomposed in the solid state at room temperature. When heated, Sodium gualenate decomposes almost completely within 1 week. It was found that a kneaded mixture of Sodium gualenate and cornstarch (weight ratio; 1:250) for tableting with water is stable. So, during production, Sodium gualenate could be stabilized using water. Sodium gualenate slightly inhibits the histamine release from rat peritoneal mast cells and strongly inhibits the leukocyte emigration induced by fMLP.(In Vivo):Sodium gualenate has been frequently used for the treatment of human gastritis. Cytoprotection is defined as the main mechanism of Sodium gualenate to protect the mucosa of the stomach and the antipeptic actions in vivo have also been shown.

Key Properties

• CAS Number: 6223-35-4
• MW: 300.35
• Purity: >98% (HPLC)
• Formula: C₁₅H₁₇NaO₃S
• SMILES: [Na+].CC(C)c1ccc(C)c2c(cc(C)c2c1)S([O-])(=O)=O
• Target: Others
• Solubility: DMSO:30 mg/mL (99.88 mM)

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Guaiazulenesulfonate sodium

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