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Sigma-1 receptor antagonist 6

SKU: orb2663646

Description

Compound 12 is a potent and selective Sigma-1 receptor (σ1R) antagonist. It exhibits significant antiallodynic efficacy in vivo, effectively reversing mechanical allodynia in rodent models of paclitaxel-induced neuropathic pain, supporting its use in neuroscience and analgesic research.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1335032-28-4
MW502.65
FormulaC32H34N6
SMILESN#CC1=C(N=C(C(C#N)=C1C=2C=CC=CC2)N(C)CC#C)NCCCC3CCN(CC=4C=CC=CC4)CC3
TargetSigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Sigma-1 receptor antagonist 6 (orb2663646)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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