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SCH-42354

SKU: orb1688942

Description

SCH-42354 is a potent, orally active neutral endopeptidase (NEP) inhibitor, derived from the prodrug SCH-42495. It enhances atrial natriuretic peptide (ANP) activity and inhibits the hydrolysis of leu-enkephalin and ANF with low nanomolar IC50 values. This compound demonstrates antihypertensive effects and is a valuable research tool for cardiovascular and neuropeptide studies in vitro and in vivo.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number144505-58-8
MW341.49
FormulaC16H23NO3S2
SMILESC([C@@H](C(N[C@@H](CCSC)C(O)=O)=O)CS)C1=C(C)C=CC=C1
TargetOthers,Neprilysin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • SCH 42495 [orb1708735]

    136511-43-8

    411.58

    C20H29NO4S2

    50 mg, 100 mg, 25 mg
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Key Properties

No computed properties available.

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Protocol Information

SCH-42354 (orb1688942)

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