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SCH 42495

SKU: orb1708735

Description

SCH 42495 is an orally bioavailable prodrug that is metabolized to the active neutral endopeptidase (NEP) inhibitor SCH 42354. This compound is used in research to study the role of NEP in cardiovascular and renal physiology, employing both in vitro enzymatic assays and in vivo pharmacological models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number136511-43-8
MW411.58
FormulaC20H29NO4S2
SMILES[C@H](CC1=C(C)C=CC=C1)(C(N[C@H](C(OCC)=O)CCSC)=O)CSC(C)=O
TargetOthers,Neprilysin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • (R)-SCH 42495 [orb1708736]

    156792-25-5

    411.58

    C20H29NO4S2

    25 mg, 50 mg, 100 mg
  • SCH-42354 [orb1688942]

    144505-58-8

    341.49

    C16H23NO3S2

    50 mg, 100 mg, 25 mg
  • SCH 42495 racemate [orb1708564]

    145841-10-7

    411.58

    C20H29NO4S2

    50 mg, 100 mg, 25 mg
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Key Properties

No computed properties available.

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Protocol Information

SCH 42495 (orb1708735)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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