RNF5 inhibitor inh-02

SKU: orb1694234

Description

Inh-02 is a selective RNF5/RMA1 ubiquitin ligase inhibitor used in cystic fibrosis research. It promotes functional rescue of F508del-CFTR in cellular models and modulates substrates like ATG4B and paxillin, providing a tool for studying CFTR trafficking and proteostasis mechanisms.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 324579-65-9
• MW: 384.5
• Purity: 99.23%
• Formula: C₂₃H₂₀N₄S
• SMILES: N=1SC(=NC(=NC=2C=CC=CC2)C=3C=CC=CC3)N(C1C)CC=4C=CC=CC4
• Target: E1/E2/E3 Enzyme,ATG
• Solubility: DMSO:80 mg/mL (208.06 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RNF5 inhibitor inh 02, RNF5 inhibitor inh02, RNF-5 inhibitor inh-02, RNF5 inhibitor inh-02

Compound Identifiers

PubChem CID

4151456