RN-9893 (hydrochloride)

SKU: orb1692989

Description

RN-9893 is a selective TRPV4 antagonist with IC50 values in the sub-micromolar range for both human and rat receptors. It effectively inhibits TRPV4 activity induced by chemical agonists or hypotonic stress in vitro, and its selectivity over other TRPV channels makes it a valuable research tool for studying TRPV4's role in pain, inflammation, and osmosensation.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2109450-40-8
• MW: 536.95
• Formula: C₂₁H₂₄ClF₃N₄O₅S
• SMILES: Cl.O=C(NC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C(C)C)C3=CC=C(C=C3N(=O)=O)C(F)(F)F
• Target: TRP/TRPV Channel,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121513879