Remodelin hydrobromide

SKU: orb1301046

Description

Remodelin hydrobromide

Research Area

Epigenetics & Chromatin, Metabolism Research

Key Properties

• CAS Number: 1622921-15-6
• MW: 363.275
• Purity: 99.43%
• Formula: C₁₅H₁₅BrN₄S
• SMILES: Br.N#CC=1C=CC(=CC1)C=2N=C(SC2)NN=C3CCCC3
• Target: Histone Acetyltransferase,RAAS
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:150 mg/mL (412.91 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (11.01 mM)

Bioactivity

• In Vivo:
  Remodelin restores nuclear morphology and enhances the resilience of the nucleus in HGPS cells by depleting LMNA through microtubule reorganization, mediated by its inhibition of NAT10.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

acetyl-transferase NAT10, migration, N-acetyltransferase, inhibit, Inhibitor, HAT, HATs, HCC, Histone Acetyltransferase, HGPS, HistoneAcetyltransferase, Remodelin, Remodelin HBR, Remodelin Hydrobromide, Remodelin hydrobromide, telomerase

Compound Identifiers

PubChem CID

86280479