Racecadotril

SKU: orb1309511

Description

Racecadotril (Acetorphan) is an enkephalinase inhibitor studied for treating acute diarrhea and gastroenteritis. Its mechanism of action and efficacy have been investigated in both in vitro enzymatic assays and in vivo animal models of intestinal secretion.

Research Area

Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 81110-73-8
• MW: 385.48
• Purity: 99.66% (May vary between batches)
• Formula: C₂₁H₂₃NO₄S
• SMILES: C(CC1=CC=CC=C1)(C(NCC(OCC2=CC=CC=C2)=O)=O)CSC(C)=O
• Target: Neprilysin,Proteasome
• Solubility: DMSO:45 mg/mL (116.74 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.19 mM);Ethanol:71 mg/mL (184.19 mM)

Bioactivity

• Target IC50:
  Enkephalinase:4.5 μM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cluster of differentiation 10, CD10, Acetorphan, Antidiarrheal, neutral, Neutral endopeptidase, NEP, Neprilysin, inhibit, Inhibitor, Endopeptidase, endopeptidase, Racecadotril

Compound Identifiers

PubChem CID

107751