Rabbit Human fibonectin Antibody

SKU: orb21229

Description

Precipitating polyclonal rabbit antiserum to human fibronectin. Fibronectin is a glycoprotein with a molecular weight of 440,000 and consists of two identical peptide chains. Its mean concentration in plasma is 330 mg/ml. Elevated plasma levels of fibronectin are observed in chronic active liver disease; decreased values are found in cases of acute leukaemia, sepsis, severe burns, acute pancreatitis, inflammatory processes, haemorrhagic shock and polytrauma. Fibronectin is also present on cell surfaces. It cab be cross-linked to the fibrin clot by the action of F XIIIA. As formation of the clot occurs approximately 50% of the plasma Fibronectin is lost. Freund's complete adjuvant is used in the first step of the immunization procedure.

Images & Validation

• Reactivity: Human

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Delipidated, heat inactivated, lyophilized, stable whole antiserum. Sodium azide 0.7 mg/ml Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled rabbit serum. No foreign proteins added.
• Disclaimer: For research use only

Quick Database Links

UniProt

P02751