R-(+)-Lansoprazole

SKU: orb1226391

Description

Dexlansoprazole is a Proton Pump Inhibitor. (In Vitro):The plasma concentrations of (R)-lansoprazole are remarkably higher in all three CYP2C19 genotype groups than those of the corresponding (S)-enantiomer. The AUC0-∞ Cmax and elimination half-life of (R)-lansoprazole are significantly greater and longer, respectively, than those of the (S)-enantiomer for all three genotype groups.

Key Properties

• CAS Number: 138530-94-6
• MW: 369.36
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₄F₃N₃O₂S
• SMILES: O=[S@@](C1=NC2=CC=CC=C2N1)CC3=NC=CC(OCC(F)(F)F)=C3C
• Target: Proton Pump
• Solubility: Water: 74 mg/mL (200.34 mM); DMSO: 74 mg/mL (200.34 mM)

Bioactivity

• In Vitro:
  The plasma concentrations of (R)-lansoprazole are remarkably higher in all three CYP2C19 genotype groups than those of the corresponding (S)-enantiomer. The AUC0-∞ Cmax and elimination half-life of (R)-lansoprazole are significantly greater and longer, respectively, than those of the (S)-enantiomer for all three genotype groups.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(+)-Lansoprazole | T-168390 | TAK-390

Quick Database Links

Gene Symbol

Proton Pump