(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11)

SKU: orb2694224

Description

(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11) is a Substance P (HY-P0201) analogue that has approximately the same effects as Substance P (HY-P0201) on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. (Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain.(Pyr5,N-Me-Phe8,Sar9)-Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats.

Images & Validation

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Key Properties

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Target	Neurokinin Receptor
Molecular Weight	880.06
Protein Sequence	{Pyr}-QF(-Me)F-Sar-LM-NH2
Purity	≥95%

Storage & Handling

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Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Neurokinin Receptor

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