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PXS-6302

PXS-6302

Catalog Number: orb1689585

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Catalog Numberorb1689585
CategorySmall Molecules
DescriptionPXS-6302
Purity98.00%
MW265.25
Biological ActivityPXS-6302 is an irreversible inhibitor of lysyl oxidase with IC50s of 3.7 μM for Bovine LOX, 3.4 μM for rh LOXL1, 0.4 μM for rh LOXL2, 1.5 μM for rh LOXL3, 0.3 μM for rh LOXL4, respectively. PXS-6302 can readily penetrate the skin, reduces collagen deposition and cross-linking, and significantly improves scar appearance without reducing tissue strength. PXS-6302 also has potentially broader applications in other fibrotic diseases.
CAS Number2584947-54-4
FormulaC10H10F3NO2S
SMILESS(C(/C(=C/CN)/F)(F)F)(=O)(=O)C1=CC=CC=C1
Storage-20°C
NoteFor research use only
  • PXS-6302 hydrochloride [orb1945022]

    99.89%

    2584947-79-3

    301.71

    C10H11ClF3NO2S

    50 mg, 25 mg, 1 mg, 5 mg, 10 mg, 100 mg, 2 mg