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PROTAC KRAS G12C degrader-1

SKU: orb2279022

Description

PROTAC KRAS G12C degrader-1 is a cereblon (CRBN)-recruiting bifunctional molecule that induces the degradation of GFP-KRAS G12C fusion proteins in cellular models. This tool compound is valuable for studying KRAS-driven oncogenesis and targeted protein degradation, supporting both in vitro and in vivo research on this critical cancer target.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW917.47
FormulaC50H54ClFN8O6
TargetPROTACs,Ras,Kras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

PROTAC KRAS G12C degrader-1 (orb2279022)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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