PROTAC ERα Degrader-2

SKU: orb1987806

Description

PROTAC ERα Degrader-2 is a heterobifunctional SNIPER molecule that recruits cIAP1 to degrade estrogen receptor α (ERα). It achieves maximal ERα degradation at 30 µM in MCF7 breast cancer cells, serving as a research tool for studying targeted protein degradation in oncology.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1351169-29-3
• MW: 763.96
• Formula: C₄₂H₆₁N₅O₈
• SMILES: C[C@@]1\2[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC/C2=N\OCC(NCCOCCOCCNC([C@@H](NC([C@H]([C@@H](CC5=CC=CC=C5)N)O)=O)CC(C)C)=O)=O)[H]
• Target: Estrogen Receptor/ERR,PROTACs,SNIPERs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

54764406