PROTAC ERα Degrader-1

SKU: orb1987784

Description

PROTAC ERα Degrader-1 is a heterobifunctional small molecule that induces the degradation of estrogen receptor alpha (ERα) by recruiting an E3 ubiquitin ligase. It is a valuable chemical tool for investigating ERα biology and targeted protein degradation in both cellular and animal models of breast cancer research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 1120.29
• Formula: C₆₆H₆₉N₇O₁₀
• SMILES: OC1=CC=C(/C(C2=CC=C(OCCN(C)C(COCCOCCNC(C3=CC=C(C(N4[C@@H](C)[C@H](NC([C@H](C)NC)=O)C(N(CC5=C(OC)C=CC6=C5C=CC=C6)C7=C4C=C(C#N)C=C7)=O)=O)C=C3)=O)=O)C=C2)=C(C8=CC=CC=C8)\CC)C=C1
• Target: PROTACs,Estrogen Receptor/ERR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

132144837