PROTAC ERα Y537S degrader-1

SKU: orb1982998

Description

PROTAC ERα Y537S degrader-1 is a heterobifunctional molecule designed to target the estrogen receptor alpha Y537S mutant for degradation. It consists of an ERα-binding ligand, an E3 ligase recruiter, and a connecting linker. This compound is a research tool for studying mutant ERα biology and targeted protein degradation in breast cancer models, both in cellular and animal studies.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2667598-05-0
• MW: 767.91
• Formula: C₄₆H₄₉N₅O₆
• SMILES: Oc1ccc2[C@H]([C@H](CCc2c1)c1ccccc1)c1ccc(cc1)N1CCC(CN2CCN(CC2)c2cc3CN(C4CCC(=O)NC4=O)C(=O)c3c3OCOc23)CC1
• Target: Estrogen Receptor/ERR,Others,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163322292