PROTAC ATR degrader-1

SKU: orb2565427

Description

ZS-7 is a potent and selective PROTAC degrader of ATR kinase with a DC50 of 0.53 µM. This small molecule tool compound is valuable for cancer research, enabling the study of ATR's role in DNA damage response pathways in both cellular and in vivo models.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2925916-30-7
• MW: 933.05
• Formula: C₄₆H₅₂N₁₂O₈S
• SMILES: S(=NC(CCC1=CN(CCCCCCCC(NC2=C3C(C(=O)N(C3=O)C4C(=O)NC(=O)CC4)=CC=C2)=O)N=N1)=O)(C)(=O)C5(CC5)C6=NC(=NC(=C6)N7[C@H](C)COCC7)C8=C9C(=NC=C8)NC=C9
• Target: PROTACs,ATM/ATR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172653085