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PMX-53

SKU: orb1699615

Description

PMX-53 is a dual-activity compound functioning as a Mas-related G-protein coupled receptor X2 (MrgX2) agonist and a complement C5a receptor (C5aR/CD88) antagonist. Research demonstrates its efficacy in reducing atherosclerotic lesions in mice, inhibiting breast cancer lung metastasis, and attenuating C5a-induced hypernociception in rat models.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetComplement System
CAS Number219639-75-5
MW896.09
FormulaC47H65N11O7
SMILESCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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PMX-53 (orb1699615)

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