PKC beta 1 Antibody

• Catalog Number: orb1731515
• Category: Antibodies
• Description: Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'.
• Species/Host: Rabbit
• Clonality: Monoclonal
• Tested applications: ICC, IP, WB
• Reactivity: Human, Rat
• Isotype: Rabbit IgG
• Immunogen: A synthetic peptide of human PKC beta 2
• Concentration: 1mg/ml
• Dilution range: IP: 1/20; WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 77 kDa; Observed MW: 77 kDa
• Entrez: 5579
• UniProt ID: P05771
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% rAlbumin
• Alternative names: PRKCB; PKCB; PRKCB1; Protein kinase C beta type; P
• Note: For research use only
• Expiration Date: 12 months from date of receipt.