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Piperazine citrate

SKU: orb1940703

Description

Piperazine citrate, an organic compound, consists of a six-membered ring, containing two nitrogen atoms at opposite positions in the ring. It used as an Anthelmintic.(In Vivo):Fifteen of 20 Wistar albino rats were treated with various doses of the anthelmintic agent piperazine citrate (15, 30, and 60 mg/kg body weight). All 20 rats were subsequently given barium chloride, 20 mg/kg. The 5 rats (25%) that did not receive piperazine citrate developed ventricular fibrillations after barium chloride was administered to them, via one of the external jugular veins, and died shortly thereafter. The remaining 75% of the rats were fully protected by all the doses of piperazine citrate employed for the study. Barium chloride did not produce any dysrhythmic phenomenon in the piperazine-protected rats. Conversely, sinus rhythm was maintained in the electrocardiogram of all the rats, with every P wave followed by a normal QRS-T complex.

Images & Validation

Key Properties

CAS Number144-29-6
MW642.66
Purity>98% (HPLC)
FormulaC24H46N6O14
SMILESC1CNCCN1.C1CNCCN1.C1CNCCN1.OC(=O)CC(O)(CC(O)=O)C(O)=O.OC(=O)CC(O)(CC(O)=O)C(O)=O
TargetInfluenza A
SolubilityIn Vitro: DMSO : 2.17 mg/mL (6.75 mM)

Bioactivity

In Vitro
Piperazine citrate is a promising scaffold with analgesic and anti-inflammatory potential. Piperazine citrate is a key substructure for antidepressants.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • Piperazine citrate [orb1307872]

    99.80% (May vary between batches)

    144-29-6

    642.65

    C24H46N6O14

    5 g, 1 g, 10 g
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Protocol Information

Piperazine citrate (orb1940703)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

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