Phenidone

SKU: orb1305951

Description

Phenidone

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience

Key Properties

• CAS Number: 92-43-3
• MW: 162.19
• Purity: 99.34%
• Formula: C₉H₁₀N₂O
• SMILES: O=C1CCN(N1)c1ccccc1
• Target: COX,Lipoxygenase
• Solubility: DMSO:99 mg/mL (610.4 mM)

Bioactivity

• In Vivo:
  Lipoxygenase inhibitor phenidone markedly attenuates angiotensin II (AII) induced vascular contractility. Phenidone was also shown to inhibit the formation of vascular lipoxygenase products and to reduce blood pressure in the AII-dependent renovascular hypertensive rat.
• In Vitro:
  Western blot analysis showed that phenidone significantly inhibited the increases in COX-1/-2 and 5-LOX in the spinal cords of rats with EAE.

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

photographic, Phenidone, pressure, inhibit, Lipoxygenase, LOX, oral, Inhibitor, hypertensive, autoimmune, blood, 1-phenyl-3-pyrazolidinone, Cyclooxygenase, COX, developer

Compound Identifiers

PubChem CID

7090