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Catalog Number | orb1308507 |
---|---|
Category | Small Molecules |
Description | Perindopril erbumine |
CAS Number | 107133-36-8 |
Purity | 99.80% |
MW | 441.61 |
SMILES | CC(C)(C)N.N1([C@@H]2[C@H](C[C@H]1C(=O)O)CCCC2)C(=O)[C@@H](N[C@H](C(=O)OCC)CCC)C |
Formula | C23H43N3O5 |
Biological Activity | Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited and diuresis and natriuresis ensue. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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