Oxiconazole nitrate

SKU: orb1309103

Description

Oxiconazole nitrate

Research Area

Infectious Disease & Virology, Metabolism Research

Key Properties

• CAS Number: 64211-46-7
• MW: 492.14
• Purity: 99.73%
• Formula: C₁₈H₁₃Cl₄N₃O·HNO₃
• SMILES: [N+](=O)([O-])O.C(=N\OCc1c(cc(cc1)Cl)Cl)(/c1c(cc(cc1)Cl)Cl)\Cn1ccnc1
• Target: Antifection,Antibiotic,Antifungal,Cytochromes P450
• Solubility: DMSO:50 mg/mL (101.6 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.06 mM)

Bioactivity

• Target IC50:
  T. tonsurans:0.25 μg/mL (MIC90)|T. rubrum:0.5 μg/mL (MIC90)
• In Vivo:
  Fusidin(Fusidate Sodium) ameliorates EAM, at least partly, through an inhibitory action on the secretion of TNF-a. It markedly attenuates clinical and histological signs of immunoinflammatory diabetes mellitus in mice given streptozotocin(SZ). The effect is dose-dependent, observed in three different strains of mice. Thus, fusidin might have an antidiabetogenic effect.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Fungal, HCT116, Inhibitor, inhibit, LSS, Cytochrome P450, CYP3A4, CYPs, colorectal cancer, 14-α Demethylase, Antifungal, Antibiotic, BALB/c nude mice, Rifampicin, Ro 13-8996, Oxiconazole, Oxiconazole Nitrate, Oxiconazole nitrate, PRDX2

Compound Identifiers

PubChem CID

9556529