ORC3L Rabbit Polyclonal Antibody

SKU: orb331176

Description

Rabbit polyclonal antibody to ORC3 also known as Origin recognition complex subunit Latheo, whose expression can be detected in the eye and duodenum but is highly expressive in the dura mater and dorsal thalamus. It is found in the nucleus. This protein is a component of the origin recognition complex (ORC) that binds origins of replication while DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Research Area

Cell Biology

Images & Validation

• Tested Applications: WB
• Reactivity: Human
• Predicted Reactivity: Bovine, Canine, Equine, Guinea pig, Mouse, Porcine, Rabbit, Rat, Yeast, Zebrafish

Key Properties

• Host: Rabbit
• Clonality: Polyclonal
• Target: ORC3
• Molecular Weight: 82kDa
• Purification: Affinity Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: 0.5 - 1 mg/ml
• Disclaimer: For research use only

Alternative Names

anti-LAT antibody, anti-LATHEO antibody, anti-ORC3 antibody, anti-ORC3L antibody

WB Suggested Anti-ORC3L Antibody, Titration: 1.0 ug/ml, Positive Control: HepG2 Whole Cell, ORC3 is supported by BioGPS gene expression data to be expressed in HepG2.

Quick Database Links

Gene Symbol

ORC3

UniProt

Q9UBD5

RefSeq (Protein):NP_862820