Omadacycline

SKU: orb1302012

Description

Omadacycline (Amadacycline) is a novel tetracycline-class antibiotic that acts by binding to the bacterial 30S ribosomal subunit, inhibiting protein synthesis. It is utilized in research for studying antibacterial mechanisms and efficacy in both in vitro and in vivo models against susceptible pathogens.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 389139-89-3
• MW: 556.65
• Purity: 99.55% (May vary between batches)
• Formula: C₂₉H₄₀N₄O₇
• SMILES: CN(C)C1C2CC3Cc4c(cc(CNCC(C)(C)C)c(O)c4C(O)=C3C(=O)C2(O)C(O)=C(C(N)=O)C1=O)N(C)C
• Target: Antibacterial|||Antibiotic|||ribosome
• Solubility: DMSO:50 mg/mL (89.82 mM);10% DMSO+90% Saline:5 mg/mL (8.98 mM)

Bioactivity

• In Vitro:
  Omadacycline had inhibitory against isolates of M. abscessus, M. chelonae, and M. fortuitum (MIC90 of 2 μg/ml, 0.25 μg/ml, and 0.5 μg/ml, respectively).
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

broad, atypical, Bacterial, anaerobic, antibacterial, Antibiotic, 30S ribosome, Amadacycline, agent, acute, community-acquired, Inhibitor, inhibit, infections, pathogens, pneumonia, Omadacycline, Gram-negative, Gram-positive, protein, spectrum, synthesis, tract, tetracycline, PTK0796, PTK-0796, PTK 0796, skin-structure, skin, urinary

Compound Identifiers

PubChem CID

54681072