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Olprinone

SKU: orb1302152

Description

Olprinone (Loprinone) is a selective PDE3 inhibitor used in research to study cardiac function and microcirculation. Its applications include investigating post-cardiopulmonary bypass hemodynamics and its anti-inflammatory effects in both in vitro and in vivo experimental models.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number106730-54-5
MW250.26
Purity99.87% (May vary between batches)
FormulaC14H10N4O
SMILESCc1[nH]c(=O)c(cc1-c1ccc2nccn2c1)C#N
TargetPDE
SolubilityDMSO:2.51 mg/mL (10.03 mM)

Bioactivity

Target IC50
PDE3:0.35 μM (IC50)|PDE2:100 μM (IC50)|PDE4:14 μM (IC50)|PDE1:150 μM (IC50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Loprinone, inhibit, Olprinone, PDE3, Inhibitor, heart, inotropic, failure, cytokine, anti-inflammatory, Phosphodiesterase (PDE), phosphodiesterase, positive, vasodilative

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Quality Guarantee

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Key Properties

No computed properties available.

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Olprinone (orb1302152)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 80.00
25 mg
$ 120.00
50 mg
$ 160.00
100 mg
$ 210.00
200 mg
$ 300.00
DispatchUsually dispatched within 3-5 working days
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