Olaparib

• Catalog Number: orb1304620
• Category: Small Molecules
• Description: Olaparib
• CAS Number: 763113-22-0
• Purity: 99.89%
• MW: 434.46
• SMILES: C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCN(C(=O)C5CC5)CC4)=C(F)C=C3
• Formula: C₂₄H₂₃FN₄O₃
• Biological Activity: Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and mitochondrial autophagy activation activity.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.