Octopamine hydrochloride

SKU: orb1224035

Description

Octopamine (OA), a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates.(In Vitro):Octopamine has a prominent role in influencing multiple physiological events: (a) as a neuromodulator, it regulates desensitization of sensory inputs, arousal, initiation, and maintenance of various rhythmic behaviors and complex behaviors such as learning and memory; (b) as a neurotransmitter, it regulates endocrine gland activity; and (c) as a neurohormone, it induces mobilization of lipids and carbohydrates. Octopamine exerts its effects by binding to specific proteins that belong to the superfamily of G protein-coupled receptors and share the structural motif of seven transmembrane domains.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 770-05-8
• MW: 189.64
• Purity: >98% (HPLC)
• Formula: C₈H₁₂CINO₂
• SMILES: OC1=CC=C(C(O)CN)C=C1.[H]Cl
• Target: Dopamine Receptor
• Solubility: Ethanol: 11 mg/mL (58.0 mM); Water: 38 mg/mL (200.37 mM); DMSO: 38 mg/mL (200.37 mM)

Bioactivity

• In Vitro:
  Octopamine has a prominent role in influencing multiple physiological events: (a) as a neuromodulator, it regulates desensitization of sensory inputs, arousal, initiation, and maintenance of various rhythmic behaviors and complex behaviors such as learning and memory; (b) as a neurotransmitter, it regulates endocrine gland activity; and (c) as a neurohormone, it induces mobilization of lipids and carbohydrates. Octopamine exerts its effects by binding to specific proteins that belong to the superfamily of G protein-coupled receptors and share the structural motif of seven transmembrane domains.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

β,4-Dihydroxyphenethylamine | Epirenor | Norfen | NSC 108685 | (±)-4-Octopamine | (±)-p-Octopamine

Quick Database Links

Gene Symbol

Dopamine Receptor