O-Desmethyl apixaban

SKU: orb1992748

Description

O-Desmethyl apixaban, the primary active metabolite of Apixaban, is a potent and reversible direct Factor Xa inhibitor. It demonstrates high selectivity with Ki values of 0.08 nM (human) and 0.17 nM (rabbit). This compound is a valuable pharmacological tool for studying anticoagulant mechanisms in both biochemical and pharmacokinetic research models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 503612-76-8
• MW: 445.47
• Formula: C₂₄H₂₃N₅O₄
• SMILES: O=C(N)C1=NN(C2=CC=C(O)C=C2)C=3C(=O)N(C4=CC=C(C=C4)N5C(=O)CCCC5)CCC13
• Target: Drug Metabolite,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10203943