Neuropilin 1 Antibody

• Catalog Number: orb1730020
• Category: Antibodies
• Description: The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ELISA, IHC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human NRP1. AA range:321-370
• Dilution range: WB: 1/500-1/1000; IHC: 1/50-1/100; ELISA: 1/10000
• Conjugation: Unconjugated
• MW: Calculated MW: 103 kDa; Observed MW: 100 kDa
• Entrez: 8829
• UniProt ID: O14786
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: NRP1; NRP; VEGF165R; Neuropilin-1; Vascular endoth
• Note: For research use only
• Expiration Date: 12 months from date of receipt.