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N-Nitrosodiethylamine

SKU: orb1940340

Description

N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the liver, nasal cavity, trachea, lung and esophagus.(In Vivo):Mice with N-Nitrosodiethylamine (25mg/kg) intraperitonially resulted in fatty liver disease leading to progress of cancer disease.

Images & Validation

Key Properties

CAS Number55-18-5
MW102.137
Purity>98% (HPLC)
FormulaC4H10N2O
SMILESCCN(CC)N=O
TargetDNA/RNA Synthesis
SolubilityIn Vitro: H2O : 100 mg/mL (979.05 mM)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information